PlagueWatch - Coronavirus

A study says taking antihistamines may reduce the risk of Covid infection. I have no idea if it's true, but given that antihistamines have been shown to be safe, I may be taking loratadine on my next trip. https://journals.asm.org/doi/10.1128/mbio.01697-24
I still have caught it and I’m on Zyrtec for about 2/3 of the year for allergies. Personally I’d bet it my colitis that has my immune system ready for a fight 24/7. I haven’t had symptoms for more than 6 hours and the symptoms are the same as a flare up for me.
 
I doubt they are strain specific. I don’t thing the mutation sites are what’s binding to light up the possible. They aren’t 100% to start with.
Yes, I agree. I think some variants may take longer to show up on tests, but they will be detected, eventually.
 
I still have caught it and I’m on Zyrtec for about 2/3 of the year for allergies. Personally I’d bet it my colitis that has my immune system ready for a fight 24/7. I haven’t had symptoms for more than 6 hours and the symptoms are the same as a flare up for me.

I take loratidine every day. And it didn’t help me avoid Covid. Small sample size though.
 
A study says taking antihistamines may reduce the risk of Covid infection. I have no idea if it's true, but given that antihistamines have been shown to be safe, I may be taking loratadine on my next trip. https://journals.asm.org/doi/10.1128/mbio.01697-24
The study looked at two antihistamines, and the effect varied significantly, with the most effective drug being activastine, which pretty much nobody in America takes.

Add me and my wife to the list of people who take antihistamines every day but have somehow managed to get Covid at least two times each.

There are enough people on antihistamines that if the usual suspects had much of a preventative effect I suspect we would have known about it by now.
 
Some interesting insights on upcoming new technology for vaccines: https://hms.harvard.edu/news/creating-next-generation-mrna-vaccines

* Harvard Medical School researchers at Boston Children’s Hospital have now developed two technologies that could make these and future mRNA vaccines more potent and longer-lasting — at smaller doses and with fewer side effects.

* Current vaccines offer short-lived immune protection, requiring frequent boosters, and stimulate less of a response in people over 60. They also can cause side effects.

* The adjuvant-vaccine boosted multiple elements of the immune response — not just antibody production, but also cytokine production and immune cell activity, each important for protection from SARS-CoV-2.

* The adjuvant-vaccine combination also produced more long-lasting immunity than the current vaccine alone. Animals receiving the adjuvant showed signs of amplified immunity even one year later. Moreover, in aged mice, the immune response with the adjuvant reached levels similar to those in young adult mice.

* The new mRNA incorporates a second technology — a so-called Multi-Organ Protection (MOP) sequence — designed to reduce side effects. Although the mRNA travels to cells throughout the body, the MOP sequence is designed to ensure that it acts only on muscle tissue.

* “Our technology gives the ability to reduce the vaccine dose but get the same level of immune response,” said Brook. “This is what’s needed for mRNA vaccines to be used more widely.”

* The team believes the technology could be adapted for other mRNA vaccines in development, such as flu vaccines. Alternatively, the optimized version of the mRNA vaccine could be given as an adjuvant together with other types of vaccines.

* They have moved on to testing it in non-human primates, whose immune systems resemble more closely those of humans, with the ultimate goal of moving into human clinical trials.
 
Vax’d! Pfizer again. I’ll wait a couple of weeks for the flu shot.

The RSV vaccine is good for 2 years? Got it last September.
I've heard from pharmacists that current FDA labeling is for one dose forever... at least until FDA recommendations change.
 
meanwhile I hit The Rover this morning, travelling service the state of VT offers to get rid of household crap items like old paint cans, solvents, whatever...first guy there since I basically got no sleep last night...
 
meanwhile I hit The Rover this morning, travelling service the state of VT offers to get rid of household crap items like old paint cans, solvents, whatever...first guy there since I basically got no sleep last night...
At least you had a late football game to watch before you were first in line
 
My SO got her Pfizer booster yesterday. A not too bad sore and a little chill, but otherwise no problems this morning. If you’ll remember, last October we got our shots the Monday after a Saturday tailgate, and she (and the Devildeacs) all got sick with Covid on Tuesday after the Saturday tailgate.

She did fall sound asleep at halftime last night so I rewatched the second half and overtime while she watched it for the first time 😎!

2-0 baby! 2-0!

We’ll wait a couple of weeks to get our flu shots.
 
Got flu shot in my right arm last night and COVID shot in my left. A tiny bit sore on the left and can't even tell I got a shot on my right. So far, no other side effects. Fingers crossed.
 
Got both Covid (Moderna) and flu in my left arm yesterday. My arm is quite sore, and I took a nap yesterday and might again today, but no actual side effects.
 
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