Not sure if this qualifies, but the missus and myself are big into word games. Boggle is a favorite. Scrabble is fun if you don't have one player that insists on taking 45 minutes for each turn.

Our favorite is Quiddler. It's a card based word game, where you draw and discard similar to fun rummy. Highly recommended.

Additionally, I'd echo those who mentioned Apples to Apples, Cards Against Humanity, Taboo, Scattergories...

Our challenge is finding games to play with just two people. Any advice on that front would be appreciated.