Hmmm, we're not going to agree on this one. (Keeping in mind this is all in good offseason talk / fun mode).
Tre destroys whatever Louisville guard you have bringing it up the court. And I do think Tre is the best player returning on either team, even though I love Nwora. You say the Duke trio that left masked team limitations -- maybe, but I also think they masked how good Tre is, and he's going to be a great college player next season with his usage going up. I disagree that their bigs are better. I think it's a wash -- Lville's bigs are better offensively, but Duke's are better defensively. And with AOC, Joey, and Jack spreading the court, our bigs don't need to do more than catch lob-dunks after Tre penetrates a spread court. Duke 70, Louisville 65.
All in all, we're probably splitting hairs between two fringe NCAA tourney teams (since we're removing the freshmen from the rosters). Both teams will need their freshmen to play well to dream big stuff.