Duke wins every bracket I fill out! This year Duke will beat Ohio State 75-73 in the Championship Game (I've had a vision) and you can take that to the bank!
I like #12 teams over the #5 teams (ODU and Arkansas this year). I pick the power conferences mainly because of the competition they have faced. For example, Indiana over Gonzaga, Vanderbilt over George Washington, Notre Dame over Winthrop, and Maryland over Davidson.
Finally, and most important, my bracket always looks like chopped liver after the first weekend.