I've done it several times. Turns out great and I've received many compliments.
I've used a 3 or 4 pound boneless pork piece, put it in a ziplock w/ some store-bought dry rub and treat it like shake and bake and shake all around so the dry rub coats the meat (have let it sit overnight; also done it just before it goes into the crock pot), and then the meat goes into the crock pot for 6 or 7 hours.
My crock pot only has high and low settings (no medium) so I usually do the first half of the time on high, the second half on low. While the meat is cooking, I don't open the lid for anything.
After it's cooked, take the meat out, chop it up (or pull it apart), get rid of all the grease/liquid in the crock pot, wash the crock pot, put the meat back into the crock pot, and then put some sauce on it. The sauce recipe I use (just found on the internet at
www.amazingribs.com):
1 cup distilled vinegar (not cider vinegar)
1/4 cup ketchup
1/4 cup apple juice
3 tablespoons brown sugar
1/2 tablespoon salt
1 teaspoon crushed red pepper
1 teaspoon finely ground black pepper
(the recipe also calls for 1 teaspoon hot sauce but I leave that out)
Whisk together and let sauce sit overnight before using.
This sauce recipe usually makes more sauce than necessary for the amount of meat -- don't want the meat swimming in sauce.